Table 5 Optimum cut-off values with the highest sensitivity and specificity

From: Early diagnosis of keratoconus using corneal biomechanics and OCT derived technologies

Parameters	FFKC vs. Normal
Parameters	AUROC	Sensitivity	Specificity	Cutoff
Posterior asymmetry (D)	0.778	0.58	0.88	0.08
Posterior asymmetry (D)	P < 0.001	0.58	0.88	0.08
CBI	0.762	0.54	0.93	0.46
CBI	P < 0.001	0.54	0.93	0.46
BAD-D	0.774	0.64	0.86	1.43
BAD-D	P < 0.001	0.64	0.86	1.43
TBI	0.759	0.64	0.86	0.25
TBI	P < 0.001	0.64	0.86	0.25
Posterior asymmetry + CBI	0.863	0.74	0.91	N/A
Posterior asymmetry + CBI	P < 0.001	0.74	0.91	N/A

FFKC = forme fruste keratoconus; AUROC = area under the receiver operating characteristic curve; CBI = Corvis biomechanical index; BAD-D = Belin/Ambrósio enhanced ectasia display total deviation; TBI = tomographic and biomechanical index

Back to article page

ISSN: 2326-0254

Contact us

General enquiries: journalsubmissions@springernature.com