Table 4 Difference in corneal nerve parameters between combined BMI categories in patients with diabetes
From: Obesity negatively impacts corneal nerves in patients with diabetes mellitus
Parameter | Underweight + Normal (n = 230) | Overweight + Class I obesity (n = 546) | Class II + III obesity (n = 31) | ANOVA P value |
|---|---|---|---|---|
CNFD (no. of fibers/mm2) | 12.7 ± 4.9 | 11.6 ± 5.4 | 9.9 ± 4.7 | 0.04 |
CNFL (total length of fibers mm/mm2) | 8.4 ± 3.1 | 8.3 ± 3.0 | 7.6 ± 2.5 | 0.01 |
CNBD (no. of branch points on main fibers/mm2) | 11.1 ± 7.6 | 11.4 ± 8.9 | 8.5 ± 6.2 | 0.03 |
CTBD (total no. of branch points/mm2) | 18.4 ± 11.1 | 19.9 ± 12.6 | 16.6 ± 9.8 | 0.04 |
CNFA (total nerve fiber area mm2/mm2) | 0.0039 ± 0.0017 | 0.0040 ± 0.0013 | 0.0038 ± 0.0013 | 0.30 |
CNFW (average nerve fiber width mm/mm2) | 0.0219 ± 0.0110 | 0.0221 ± 0.0012 | 0.0221 ± 0.0012 | 0.08 |
CFracDim | 1.39 ± 0.03 | 1.39 ± 0.04 | 1.38 ± 0.04 | 0.07 |
Corneal sensitivity (cm) | 28.5 ± 2.2 | 28.7 ± 2.8 | 28.1 ± 1.9 | 0.15 |