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Table 4 Relationship between optic disc morphology and OCT parameters—subgroup analysis

From: Exploring optical coherence tomography parameters in eyes with myopic tilted disc

Sectors

Temporal group (n = 335)

Nasal group (n = 195)

Optic disc torsion angle (°)a

OCT horizontal tilt angle (°)b

Ovality indexc

Optic disc torsion

angle (°)a

OCT horizontal tilt angle (°)b

Ovality indexc

Coefficient

(95% CI)

P value

Coefficient

(95% CI)

P value

Coefficient

(95% CI)

P value

Coefficient

(95% CI)

P value

Coefficient

(95% CI)

P value

Coefficient

(95% CI)

P value

Macular ganglion cell inner-plexiform layer (GCIPL) (μm)

 ST

0.01

(− 0.03, 0.05)

0.58

− 0.08

(− 0.16, − 0.01)

0.04

− 0.67

(− 5.57, 4.23)

0.79

0.02

(− 0.02, 0.05)

0.33

− 0.04

(− 0.11, 0.04)

0.32

− 4.35

(− 10.44, 1.75)

0.16

 S

0.40 × 10−2

(− 0.03, 0.04)

0.81

− 0.07

(− 0.13, − 0.01)

0.03

− 1.90

(− 5.94, 2.14)

0.36

0.01

(− 0.03, 0.04)

0.79

− 0.01

(− 0.07, 0.06)

0.81

− 6.97

(− 13.04, − 0.91)

0.02

 SN

0.10 × 10−2

(− 0.04, 0.04)

0.96

− 0.06

(− 0.14, 0.02)

0.14

− 3.24

(− 7.80, 1.33)

0.17

0.01

(− 0.22, 0.05)

0.51

− 0.03

(− 0.10, 0.04)

0.44

− 7.47

(− 13.95, − 0.98)

0.02

 IT

0.02

(− 0.02, 0.06)

0.35

− 0.02

(− 0.11, 0.08)

0.76

− 2.72

(− 8.21, 2.79)

0.33

0.01

(− 0.03, 0.05)

0.52

− 0.04

(− 0.15, 0.07)

0.52

− 3.76

(− 12.52, 4.99)

0.40

 I

− 0.10 × 10−2

(− 0.04, 0.03)

0.94

− 0.01

(− 0.09, 0.08)

0.90

− 3.06

(− 7.23, 1.11)

0.15

− 0.10 × 10−2

(− 0.04, 0.04)

0.95

− 0.03

(− 0.10, 0.05)

0.46

− 4.20

(− 10.39, 1.98)

0.18

 IN

0.10 × 10−2

(− 0.04, 0.04)

0.96

− 0.06

(− 0.16, 0.04)

0.23

− 2.06

(− 6.97, 2.86)

0.41

0.30 × 10−2

(− 0.03, 0.04)

0.88

− 0.03

(− 0.13, 0.06)

0.49

− 1.94

(− 8.74, 4.86)

0.58

Peripapillary retinal nerve fiber layer (RNFL) (μm)

 p1

− 0.02

(− 0.17, 0.13)

0.79

− 0.49

(− 0.84, − 0.15)

< 0.01

− 50.26

(− 71.63, − 28.88)

< 0.01

0.13

(− 0.06, 0.31)

0.19

− 0.31

(− 0.71, 0.10)

0.14

− 33.31

(− 70.53, 3.91)

0.08

 p2

0.11

(− 0.01, 0.23)

0.05

− 0.30

(− 0.58, − 0.03)

0.03

− 30.55

(− 47.93, − 13.17)

< 0.01

0.07

(− 0.11, 0.25)

0.42

− 0.25

(− 0.56, 0.06)

0.11

− 35.25

(− 61.46, − 9.05)

0.01

 p3

0.04

(− 0.04, 0.13)

0.34

− 0.22

(− 0.42, − 0.03)

0.02

− 22.09

(− 36.82, − 7.37)

< 0.01

0.07

(− 0.06, 0.20)

0.27

0.02

(− 0.25, 0.28)

0.91

− 27.75

(− 49.81, − 5.69)

0.01

 p4

0.09

(− 0.01, 0.20)

0.08

− 0.24

(− 0.47, − 0.02)

0.04

− 30.98

(− 43.26, − 18.70)

< 0.01

0.13

(− 0.01, 0.26)

0.08

− 0.04

(− 0.27, 0.20)

0.76

− 36.95

(− 61.03, − 12.88)

< 0.01

 p5

0.12

(− 0.05, 0.28)

0.17

− 0.45

(− 0.83, − 0.08)

0.02

− 30.86

(− 52.69, − 9.03)

< 0.01

0.03

(− 0.23, 0.29)

0.84

− 0.17

(− 0.55, 0.21)

0.39

− 49.60

(− 82.72, − 16.48)

< 0.01

 p6

0.13

(− 0.06, 0.32)

0.17

− 0.34

(− 0.77, 0.08)

0.11

− 8.76

(− 32.67, 15.16)

0.47

0.06

(− 0.21, 0.34)

0.65

− 0.20

(− 0.65, 0.26)

0.39

− 30.37

(− 72.31, 11.57)

0.16

 p7

− 0.18

(− 0.35, − 0.01)

0.04

− 0.17

(− 0.63, 0.29)

0.46

22.39

(− 1.93, 46.71)

0.07

− 0.08

(− 0.32, 0.17)

0.54

0.07

(− 0.53, 0.66)

0.82

12.43

(− 33.82, 58.67)

0.60

 p8

− 0.18

(− 0.32, − 0.04)

0.01

− 0.18

(− 0.52, 0.17)

0.32

29.02

(9.81, 48.22)

< 0.01

− 0.14

(− 0.35, 0.07)

0.18

− 0.11

(− 0.53, 0.30)

0.60

45.73

(1.06, 90.39)

0.05

 p9

− 0.05

(− 0.16, 0.06)

0.40

− 0.26

(− 0.51, − 0.01)

0.05

34.57

(18.52, 50.61)

< 0.01

− 0.08

(− 0.19, 0.03)

0.15

0.2 × 10−2

(− 0.21, 0.21)

0.99

16.98

(− 6.49, 40.44)

0.16

 p10

− 0.06

(− 0.23, 0.11)

0.48

− 0.14

(− 0.54, 0.25)

0.48

56.89

(33.37, 80.41)

< 0.01

− 0.16

(− 0.33, 0.01)

0.06

0.02

(− 0.35, 0.39)

0.91

14.94

(− 24.00, 53.87)

0.45

 p11

− 0.16

(− 0.32, 0.01)

0.06

− 0.23

(− 0.65, 0.18)

0.27

1.73

(− 19.49, 22.94)

0.87

− 0.14

(− 0.30, 0.02)

0.10

− 0.08

(− 0.49, 0.34)

0.73

3.53

(− 35.62, 42.68)

0.86

 p12

− 0.09

(− 0.31, 0.12)

0.40

− 0.56

(− 0.95, − 0.17)

< 0.01

− 29.46

(− 50.49, − 8.43)

< 0.01

0.07

(− 0.13, 0.26)

0.51

− 0.19

(− 0.62, 0.24)

0.38

8.60

(− 25.88, 43.09)

0.63

  1. OCT = optical coherence tomography; CI = confidence interval; SN = superonasal; IN = inferonasal; I = inferior; IT = inferotemporal; ST = superotemporal; S = superior
  2. The p1–p12 represent the 12 segmentations of RNFL in clockwise and anti-clockwise directions for the right and left eye, respectively
  3. Generalized estimation equation adjusted for age, axial length and the other myopic tilted disc parameters (i.e., additionally adjusted for aOCT horizontal tilt angle and ovality index, boptic disc torsion angle and ovality index, and coptic disc torsion angle and OCT horizontal tilt angle)
  4. P values in bold indicate statistical significance
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Eye and Vision

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