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Table 1 Comparisons of general characteristics among highly myopic eyes with C0, C1 and C2

From: Choroidal vascular changes in early-stage myopic maculopathy from deep learning choroidal analysis: a hospital-based SS-OCT study

Characteristics

No macular

lesions (C0)

Tessellated

fundus (C1)

Diffuse chorioretinal

atrophy (C2)

P value

(All)

P value

(C2–C1)

P value

(C2–C0)

P value

(C1–C0)

Participant characteristics

 No. of eyes (%)

94 (6.6)

1077 (76.0)

247 (17.4)

    

 Age (years)

32.8 ± 10.4

35.1 ± 9.6

39.1 ± 10.1

 < 0.001*

 < 0.001

 < 0.001

0.097

 Gender (male/female)

23 / 71

339 / 738

70 / 177

0.267†

 > 0.05

 > 0.05

 > 0.05

 Height (cm)

162.7 ± 9.3

162.5 ± 8.1

161.0 ± 7.6

0.025*

0.023

0.360

1.000

 Weight (kg)

62.5 ± 12.5

59.8 ± 10.8

59.9 ± 9.5

0.138*

1.000

0.209

0.142

 SBP (mmHg)

116.5 ± 13.4

114.4 ± 14.1

114.7 ± 15.2

0.329*

1.000

0.875

0.415

 DBP (mmHg)

68.0 ± 10

66.8 ± 10.1

67.7 ± 10.9

0.279*

0.676

1.000

0.723

Ocular biological parameters

 No. of eyes (%)

94 (6.6)

1077 (76.0)

247 (17.4)

    

 AL (mm)

26.33 ± 1.02

26.79 ± 1.02

27.90 ± 1.20

 < 0.001*

 < 0.001

 < 0.001

 < 0.001

 CCT (μm)

545 ± 32

540 ± 31

545 ± 33

0.037*

0.093

1.000

0.304

 ACD (mm)

3.63 ± 0.31

3.57 ± 0.29

3.56 ± 0.27

0.165*

1.000

0.199

0.207

 LT (mm)

3.84 ± 0.33

3.87 ± 0.36

3.94 ± 0.35

0.012*

0.023

0.044

1.000

 Corneal curvature (D)

44.1 ± 1.6

43.8 ± 1.4

43.6 ± 1.5

0.029*

0.149

0.039

0.348

 IOP (mmHg)

15.0 ± 2.6

14.4 ± 2.8

14.5 ± 2.8

0.127*

1.000

0.334

0.127

 SER (D)

 − 7.37 ± 1.23

 − 8.06 ± 1.69

 − 10.11 ± 2.69

 < 0.001*

 < 0.001

 < 0.001

 < 0.001

 BCVA (logMAR)

 − 0.028 ± 0.055

 − 0.028 ± 0.056

 − 0.007 ± 0.077

 < 0.001*

 < 0.001

0.012

1.000

Visual function

 No. of eyes (%)

69 (5.6)

942 (77.1)

211 (17.3)

    

 VFI (%)

97 ± 2

96 ± 5

94 ± 6

 < 0.001*

 < 0.001

 < 0.001

0.044

 MD (dB)

 − 3.13 ± 1.73

 − 3.48 ± 2.23

 − 4.92 ± 2.61

 < 0.001*

 < 0.001

 < 0.001

0.430

 PSD (dB)

2.18 ± 1.42

2.32 ± 1.61

3.40 ± 1.93

 < 0.001*

 < 0.001

 < 0.001

1.000

  1. Data presented are mean ± SDs. Visual field test with fixation loss < 20%, false positive errors and false negative errors < 15% were included in the analysis of visual function
  2. SBP = systolic blood pressure; DBP = diastolic blood pressure; AL = axial length; CCT = central corneal thickness; ACD = anterior chamber depth; LT = lens thickness; IOP = intraocular pressure; SER = spherical equivalent refractive; LogMAR = logarithm of the minimum angle of resolution; VFI = visual field index; MD = mean deviation; PSD = pattern standard deviation
  3. *P values were determined by GEE, and Bonferroni adjustments for multiple comparisons were applied to pairwise comparisons. †P values were determined by Pearson’s χ2 test, and Bonferroni adjustments for multiple comparisons were applied to pairwise comparisons