Table 2 Parafoveal thickness in each retinal layer at each visit

GCC (μm)

 Baseline

114.2 ± 15.6

104.2 ± 25.4

0.022

 First year

112.7 ± 15.6

98.3 ± 22.1

 Second year

112.9 ± 12.6

95.8 ± 24.2

 Third year

113.1 ± 11.2

90.6 ± 20.8

P value^†

0.695

< 0.001

INL (μm)

 Baseline

40.7 ± 3.7

41.6 ± 8.3

0.466

 First year

40.7 ± 3.6

39.4 ± 8.4

 Second year

40.4 ± 3.6

38.3 ± 9.5

 Third year

40.0 ± 3.7

37.2 ± 9.1

P value^†

0.084

< 0.001

OPL (μm)

 Baseline

33.3 ± 4.7

35.5 ± 7.8

0.080

 First year

32.1 ± 4.2

33.6 ± 7.7

 Second year

32.8 ± 4.5

32.5 ± 7.7

 Third year

33.2 ± 4.8

32.3 ± 7.1

P value^†

0.783

< 0.001

ONL (μm)

 Baseline

69.3 ± 9.7

69.9 ± 15.9

0.817

 First year

70.3 ± 9.8

65.6 ± 13.9

 Second year

69.7 ± 10.2

62.6 ± 12.5

 Third year

68.8 ± 10.8

62.0 ± 14.2

P value^†

0.295

< 0.001

PRL (μm)

 Baseline

66.8 ± 2.5

66.5 ± 1.9

0.566

 First year

66.6 ± 2.4

66.7 ± 2.5

 Second year

65.9 ± 5.4

66.7 ± 2.8

 Third year

66.6 ± 2.3

66.6 ± 3.1

P value^†

0.318

0.863

RPE (μm)

 Baseline

15.4 ± 1.9

15.3 ± 4.2

0.814

 First year

15.5 ± 2.0

15.5 ± 3.5

 Second year

15.5 ± 2.4

16.3 ± 5.5

 Third year

15.5 ± 1.9

16.1 ± 6.3

P value^†

0.991

0.092