Fig. 1
From: Efficacy of RCI001 as a therapeutic candidate of dry eye disease in a modified mixed dry eye model
Comparison of ocular surface staining and tear secretion before and after treatment with RCI001. a Representative images of ocular surface staining of BALB/c mice. b NEI corneal staining score was significantly lower in the RCI001 group than in the PBS group (P < 0.01). NEI corneal score improved significantly in the RCI001 group on Day 7 (P < 0.01). c Tear secretion was significantly increased in the RCI001 group on Day 7 (P < 0.001) and tear secretion rate was significantly higher in the RCI001 group than in the PBS group on Day 7 (P < 0.001). D, day; NEI, National Eye Institute; PBS, phosphate buffered saline; RCI, RCI001. Data are expressed as mean ± standard error of the mean. ***P < 0.001, Mann–Whitney U and Wilcoxon signed-rank tests, n = 12 per group